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High-Throughput Analysis of NF-κB Dynamics in Single Cells Reveals Basal Nuclear Localization of NF-κB and Spontaneous Activation of Oscillations

NF-κB is a transcription factor that upon activation undergoes cycles of cytoplasmic-to-nuclear and nuclear-to-cytoplasmic transport, giving rise to so called “oscillations”. In turn, oscillations tune the transcriptional output. Since a detailed understanding of oscillations requires a systems biol...

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Detalhes bibliográficos
Main Authors: Zambrano, Samuel, Bianchi, Marco E., Agresti, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942427/
https://ncbi.nlm.nih.gov/pubmed/24595030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090104
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