High content, high-throughput screening for small molecule inducers of NF-κB translocation

NF-κB is an important mediator of immune activity and its activation is essential in mounting immune response to pathogens. Here, we describe the optimization and implementation of a high-throughput screening platform that utilizes high content imaging and analysis to monitor NF-κB nuclear transloca...

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Bibliographic Details
Published in:PLoS One
Main Authors: Njikan, Samuel, Manning, Alyssa J., Ovechkina, Yulia, Awasthi, Divya, Parish, Tanya
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023200/
https://ncbi.nlm.nih.gov/pubmed/29953522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199966
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