Automated Analysis of NF-κB Nuclear Translocation Kinetics in High-Throughput Screening

Nuclear entry and exit of the NF-κB family of dimeric transcription factors plays an essential role in regulating cellular responses to inflammatory stress. The dynamics of this nuclear translocation can vary significantly within a cell population and may dramatically change e.g. upon drug exposure....

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Bibliographic Details
Main Authors: Di, Zi, Herpers, Bram, Fredriksson, Lisa, Yan, Kuan, van de Water, Bob, Verbeek, Fons J., Meerman, John H. N.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531459/
https://ncbi.nlm.nih.gov/pubmed/23300644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052337
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