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Diverse amide analogs of sulindac for cancer treatment and prevention
Sulindac is a non-steroidal anti-inflammatory drug (NSAID) that has shown significant anticancer activity. Sulindac sulfide amide (1) possessing greatly reduced COX-related inhibition relative to sulindac displayed in vivo antitumor activity that was comparable to sulindac in a human colon tumor xen...
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| Publié dans: | Bioorg Med Chem Lett |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022754/ https://ncbi.nlm.nih.gov/pubmed/28935266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.09.022 |
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