Amine Containing Analogs of Sulindac for Cancer Prevention

BACKGROUND: Sulindac belongs to the chemically diverse family of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) that effectively prevent adenomatous colorectal polyps and colon cancer, especially in patients with familial adenomatous polyposis. Sulindac sulfide amide (SSA), an amide analog of sulind...

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Bibliografiske detaljer
Udgivet i:Open Med Chem J
Main Authors: Mathew, Bini, Hobrath, Judith V., Connelly, Michele C., Guy, R. Kiplin, Reynolds, Robert C.
Format: Artigo
Sprog:Inglês
Udgivet: Bentham Open 2018
Fag:
Medicinal Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817852/
https://ncbi.nlm.nih.gov/pubmed/29492166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501812010001
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