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A Small Diversity Library of α-Methyl Amide Analogs of Sulindac for Probing Anticancer Structure-Activity Relationships

Non-steroidal anti-inflammatory drugs (NSAIDs) have a variety of potential indications that include management of pain and inflammation as well as chemoprevention and/or treatment of cancer. Furthermore, a specific form of ibuprofen, dexibuprofen or the S-(+) form, shows interesting neurological act...

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Bibliographic Details
Published in:Bioorg Med Chem Lett
Main Authors: Mathew, Bini, Snowden, Timothy S., Connelly, Michele C., Guy, R. Kiplin, Reynolds, Robert C.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081960/
https://ncbi.nlm.nih.gov/pubmed/29776741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.05.023
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