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Lipid-Exchange in Nanodiscs Discloses Membrane Boundaries of Cytochrome-P450 Reductase
Lipids are critical for the function of membrane proteins. NADPH-cytochrome-P450-reductase, the sole electron transferase for microsomal oxygenases, possesses a conformational dynamics entwined with its topology. Here, we use peptide-nanodiscs to unveil cytochrome-P450-reductase’s lipid boundaries,...
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| Pubblicato in: | Chem Commun (Camb) |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022741/ https://ncbi.nlm.nih.gov/pubmed/29863198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc02003e |
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