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Membrane Environment Drives Cytochrome P450’s Spin Transition and its Interaction with Cytochrome b5
Heme’s spin-multiplicity is key in determining the enzymatic function of cytochrome P450 (cytP450). The origin of the low-spin state in ferric P450 is still under debate. Here, we report the first experimental demonstration of P450’s membrane interaction altering its spin equilibrium which is accomp...
Shranjeno v:
| izdano v: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5710748/ https://ncbi.nlm.nih.gov/pubmed/29143058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc07520k |
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