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Membrane Environment Drives Cytochrome P450’s Spin Transition and its Interaction with Cytochrome b5

Heme’s spin-multiplicity is key in determining the enzymatic function of cytochrome P450 (cytP450). The origin of the low-spin state in ferric P450 is still under debate. Here, we report the first experimental demonstration of P450’s membrane interaction altering its spin equilibrium which is accomp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Commun (Camb)
Egile Nagusiak: Ravula, Thirupathi, Barnaba, Carlo, Mahajan, Mukesh, Anantharamaiah, G.M., Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710748/
https://ncbi.nlm.nih.gov/pubmed/29143058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc07520k
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