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Lipid-Exchange in Nanodiscs Discloses Membrane Boundaries of Cytochrome-P450 Reductase

Lipids are critical for the function of membrane proteins. NADPH-cytochrome-P450-reductase, the sole electron transferase for microsomal oxygenases, possesses a conformational dynamics entwined with its topology. Here, we use peptide-nanodiscs to unveil cytochrome-P450-reductase’s lipid boundaries,...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Barnaba, Carlo, Ravula, Thirupathi, Medina-Meza, Ilce G., Im, Sang-Choul, Anantharamaiah, G. M., Waskell, Lucy, Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022741/
https://ncbi.nlm.nih.gov/pubmed/29863198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc02003e
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