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AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing

MOTIVATION: Unique molecular identifiers (UMIs) are added to DNA fragments before PCR amplification to discriminate between alleles arising from the same genomic locus and sequencing reads produced by PCR amplification. While computational methods have been developed to take into account UMI informa...

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Publicat a:Bioinformatics
Autors principals: Clement, Kendell, Farouni, Rick, Bauer, Daniel E, Pinello, Luca
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022702/
https://ncbi.nlm.nih.gov/pubmed/29949956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty264
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