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Incorporation of Unique Molecular Identifiers (UMIs) into Unique Dual Sample Indexing (UDI) Improves the Accuracy of Quantitative NGS

The use of Unique Molecular Identifiers has become increasingly popular and offer a multitude of advantages especially when paired with unique dual sample indexing. Two major factors affecting sequencing accuracy are PCR duplication arising from amplification of library molecules and errors introduc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biomol Tech
Main Authors: Cormier, Melissa, Liu, Pingfang, Song, Chen, Posfai, Dora, Krishnan, Keerthana, McKay, Karen, Sun, Jian, Naishadham, Gautam, Langhorst, Bradley, Dimalanta, Eileen, Davis, Theodore
Format: Artigo
Jezik:Inglês
Izdano: Association of Biomolecular Resource Facilities 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424687/
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