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Protein threading using residue co-variation and deep learning

MOTIVATION: Template-based modeling, including homology modeling and protein threading, is a popular method for protein 3D structure prediction. However, alignment generation and template selection for protein sequences without close templates remain very challenging. RESULTS: We present a new metho...

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Publicat a:Bioinformatics
Autors principals: Zhu, Jianwei, Wang, Sheng, Bu, Dongbo, Xu, Jinbo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022550/
https://ncbi.nlm.nih.gov/pubmed/29949980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty278
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