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The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation

BACKGROUND: The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and differentiation. However, the precise molecular mechanism underlying pioneer factor activity remains poorly understood. We recently reporte...

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Pubblicato in:Epigenetics Chromatin
Autori principali: Fuglerud, Bettina M., Ledsaak, Marit, Rogne, Marie, Eskeland, Ragnhild, Gabrielsen, Odd S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022509/
https://ncbi.nlm.nih.gov/pubmed/29954426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0208-y
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