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The pioneer factor activity of c-Myb involves recruitment of p300 and induction of histone acetylation followed by acetylation-induced chromatin dissociation

BACKGROUND: The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and differentiation. However, the precise molecular mechanism underlying pioneer factor activity remains poorly understood. We recently reporte...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Fuglerud, Bettina M., Ledsaak, Marit, Rogne, Marie, Eskeland, Ragnhild, Gabrielsen, Odd S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022509/
https://ncbi.nlm.nih.gov/pubmed/29954426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0208-y
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