Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB

The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB levels. Despite much accumulated molecular knowledge of MYB, we still lack a com...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Lemma, Roza B., Ledsaak, Marit, Fuglerud, Bettina M., Sandve, Geir Kjetil, Eskeland, Ragnhild, Gabrielsen, Odd S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076236/
https://ncbi.nlm.nih.gov/pubmed/33903675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88516-w
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