Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway

Puerarin suppresses autophagy to alleviate cerebral ischemia/reperfusion injury, and accumulating evidence indicates that the AMPK-mTOR signaling pathway regulates the activation of the autophagy pathway through the coordinated phosphorylation of ULK1. In this study, we investigated the mechanisms u...

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Bibliographic Details
Published in:Neural Regen Res
Main Authors: Wang, Jin-Feng, Mei, Zhi-Gang, Fu, Yang, Yang, Song-Bai, Zhang, Shi-Zhong, Huang, Wei-Feng, Xiong, Li, Zhou, Hua-Jun, Tao, Wei, Feng, Zhi-Tao
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6022469/
https://ncbi.nlm.nih.gov/pubmed/29926825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.233441
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