Deptor protects against myocardial ischemia-reperfusion injury by regulating the mTOR signaling and autophagy
Abstract Deptor knockout mice were constructed by crossing Deptor Floxp3 mice with myh6 Cre mice, establishing a myocardial ischemia-reperfusion (I/R) model. Deptor knockout mice exhibited significantly increased myocardial infarction size and increased myocardial apoptosis in vivo. ELISA analysis i...
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| Hoofdauteurs: | , , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2024-12-01
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| Reeks: | Cell Death Discovery |
| Online toegang: | https://doi.org/10.1038/s41420-024-02263-1 |
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