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LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies
BACKGROUND: To date, genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants among a variety of traits/diseases, shedding light on the genetic architecture of complex disease. The polygenicity of complex diseases is a widely accepted phenomenon throu...
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| Publicado no: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022345/ https://ncbi.nlm.nih.gov/pubmed/29954342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4851-2 |
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