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GPA: A Statistical Approach to Prioritizing GWAS Results by Integrating Pleiotropy and Annotation

Results from Genome-Wide Association Studies (GWAS) have shown that complex diseases are often affected by many genetic variants with small or moderate effects. Identifications of these risk variants remain a very challenging problem. There is a need to develop more powerful statistical methods to l...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chung, Dongjun, Yang, Can, Li, Cong, Gelernter, Joel, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230845/
https://ncbi.nlm.nih.gov/pubmed/25393678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004787
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