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HC2091 Kills Mycobacterium tuberculosis by Targeting the MmpL3 Mycolic Acid Transporter

Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, is a deadly disease that requires a long course of treatment. The emergence of drug-resistant strains has driven efforts to discover new small molecules that can kill the bacterium. Here, we report characterizations of th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zheng, Huiqing, Williams, John T., Coulson, Garry B., Haiderer, Elizabeth R., Abramovitch, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021632/
https://ncbi.nlm.nih.gov/pubmed/29661875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02459-17
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