Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3

In recent years, whole-cell-based screens for novel small molecule inhibitors active against Mycobacterium tuberculosis in culture followed by the whole-genome sequencing of spontaneous resistant mutants have identified multiple chemical scaffolds thought to kill the bacterium through the inactivati...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Li, Wei, Obregón-Henao, Andrés, Wallach, Joshua B., North, E. Jeffrey, Lee, Richard E., Gonzalez-Juarrero, Mercedes, Schnappinger, Dirk, Jackson, Mary
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Susceptibility
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997843/
https://ncbi.nlm.nih.gov/pubmed/27297488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00826-16
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