Improved hybridisation potential of oligonucleotides comprising O-methylated anhydrohexitol nucleoside congeners

The hybridising potential of anhydrohexitol nucleoside analogues (HNAs) is well documented, but tedious synthesis of the monomers hampers their development. In a search for better analogues, the synthesis of two new methylated anhydrohexitol congeners 1 and 2 was accomplished and the physico-chemica...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Van Aerschot, A., Meldgaard, M., Schepers, G., Volders, F., Rozenski, J., Busson, R., Herdewijn, P.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.20.4187
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