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Improved hybridisation potential of oligonucleotides comprising O-methylated anhydrohexitol nucleoside congeners

The hybridising potential of anhydrohexitol nucleoside analogues (HNAs) is well documented, but tedious synthesis of the monomers hampers their development. In a search for better analogues, the synthesis of two new methylated anhydrohexitol congeners 1 and 2 was accomplished and the physico-chemica...

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Publicat a:Nucleic Acids Res
Autors principals: Van Aerschot, A., Meldgaard, M., Schepers, G., Volders, F., Rozenski, J., Busson, R., Herdewijn, P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600707/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.20.4187
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