Improved hybridisation potential of oligonucleotides comprising O-methylated anhydrohexitol nucleoside congeners

The hybridising potential of anhydrohexitol nucleoside analogues (HNAs) is well documented, but tedious synthesis of the monomers hampers their development. In a search for better analogues, the synthesis of two new methylated anhydrohexitol congeners 1 and 2 was accomplished and the physico-chemica...

Description complète

Détails bibliographiques

Publié dans:	Nucleic Acids Res
Auteurs principaux:	Van Aerschot, A., Meldgaard, M., Schepers, G., Volders, F., Rozenski, J., Busson, R., Herdewijn, P.
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.20.4187
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!