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Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides

Several reverse transcriptases were studied for their ability to accept anhydrohexitol triphosphates, having a conformationally restricted six-membered ring, as substrate for template-directed synthesis of HNA. It was found that AMV, M-MLV, M-MLV (H(–)), RAV2 and HIV-1 reverse transcriptases were ab...

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Autors principals: Vastmans, Karen, Froeyen, Matheus, Kerremans, Luc, Pochet, Sylvie, Herdewijn, Piet
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55830/
https://ncbi.nlm.nih.gov/pubmed/11470872
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