Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice

Mutations in genes involved in the production, migration, or differentiation of cortical neurons often lead to malformations of cortical development (MCDs). However, many genetic mutations involved in MCD pathogenesis remain unidentified. Here we developed a genetic screening paradigm based on trans...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Lu, I-Ling, Chen, Chien, Tung, Chien-Yi, Chen, Hsin-Hung, Pan, Jia-Ping, Chang, Chia-Hsiang, Cheng, Jia-Shing, Chen, Yi-An, Wang, Chun-Hung, Huang, Chia-Wei, Kang, Yi-Ning, Chang, Hsin-Yun, Li, Lei-Li, Chang, Kai-Ping, Shih, Yang-Hsin, Lin, Chi-Hung, Kwan, Shang-Yeong, Tsai, Jin-Wu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021418/
https://ncbi.nlm.nih.gov/pubmed/29950674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04880-8
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