Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice

Mutations in genes involved in the production, migration, or differentiation of cortical neurons often lead to malformations of cortical development (MCDs). However, many genetic mutations involved in MCD pathogenesis remain unidentified. Here we developed a genetic screening paradigm based on trans...

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Published in:Nat Commun
Main Authors: Lu, I-Ling, Chen, Chien, Tung, Chien-Yi, Chen, Hsin-Hung, Pan, Jia-Ping, Chang, Chia-Hsiang, Cheng, Jia-Shing, Chen, Yi-An, Wang, Chun-Hung, Huang, Chia-Wei, Kang, Yi-Ning, Chang, Hsin-Yun, Li, Lei-Li, Chang, Kai-Ping, Shih, Yang-Hsin, Lin, Chi-Hung, Kwan, Shang-Yeong, Tsai, Jin-Wu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021418/
https://ncbi.nlm.nih.gov/pubmed/29950674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04880-8
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