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Transposon-mediated mutagenesis of somatic cells in the mouse for cancer gene identification

To successfully treat cancer we will likely need a much more detailed understanding of the genes and pathways meaningfully altered in individual cancer cases. One method for achieving this goal is to derive cancers in model organisms using unbiased forward genetic screens that allow cancer gene cand...

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Detalhes bibliográficos
Autor principal: Largaespada, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806649/
https://ncbi.nlm.nih.gov/pubmed/19607923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.07.002
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