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Transposon-Mediated Mutagenesis in Somatic Cells: Identification of Transposon-Genomic DNA Junctions
Understanding the genetic basis for tumor formation is crucial for treating cancer. Forward genetic screens using insertional mutagenesis technologies have identified many important tumor suppressor genes and oncogenes in mouse models of human cancer. Traditionally, retroviruses have been used for t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517914/ https://ncbi.nlm.nih.gov/pubmed/18370070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-232-8_7 |
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