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Evaluating Risks of Insertional Mutagenesis by DNA Transposons in Gene Therapy
Investigational therapy can be successfully undertaken using viral- and non-viral-mediated ex vivo gene transfer. Indeed, recent clinical trials have established the potential for genetically modified T cells to improve and restore health. Recently the Sleeping Beauty (SB) transposon/transposase sys...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3602164/ https://ncbi.nlm.nih.gov/pubmed/23313630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2012.12.005 |
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