Somatic Mutagenesis with a Sleeping Beauty Transposon System Leads to Solid Tumor Formation in Zebrafish

Large-scale sequencing of human cancer genomes and mouse transposon-induced tumors has identified a vast number of genes mutated in different cancers. One of the outstanding challenges in this field is to determine which genes, when mutated, contribute to cellular transformation and tumor progressio...

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Autori principali: McGrail, Maura, Hatler, Julia M., Kuang, Xianyan, Liao, Hsin-Kai, Nannapaneni, Kishore, Noack Watt, Kristin E., Uhl, Juli D., Largaespada, David A., Vollbrecht, Erik, Scheetz, Todd E., Dupuy, Adam J., Hostetter, Jesse M., Essner, Jeffrey J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080878/
https://ncbi.nlm.nih.gov/pubmed/21533036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018826
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