Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth

Despite recent progress in diagnosis and treatment, survival for children with high-risk metastatic neuroblastoma is still poor. Prostaglandin E(2) (PGE(2))-driven inflammation promotes tumor growth, immune suppression, angiogenesis and resistance to established cancer therapies. In neuroblastoma, c...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Kock, Anna, Larsson, Karin, Bergqvist, Filip, Eissler, Nina, Elfman, Lotta H.M., Raouf, Joan, Korotkova, Marina, Johnsen, John Inge, Jakobsson, Per-Johan, Kogner, Per
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021299/
https://ncbi.nlm.nih.gov/pubmed/29804818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.05.008
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