Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells

There is strong evidence for a role of prostaglandin E(2) (PGE(2)) in cancer cell proliferation and tumor development. In PGE(2) biosynthesis, cyclooxygenases (COX-1/COX-2) convert arachidonic acid to PGH(2), which can be isomerized to PGE(2) by microsomal PGE-synthase-1 (MPGES-1). The human prostat...

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Dades bibliogràfiques
Autors principals: Hanaka, Hiromi, Pawelzik, Sven-Christian, Johnsen, John Inge, Rakonjac, Marija, Terawaki, Kan, Rasmuson, Agnes, Sveinbjörnsson, Baldur, Schumacher, Martin C., Hamberg, Mats, Samuelsson, Bengt, Jakobsson, Per-Johan, Kogner, Per, Rådmark, Olof
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768589/
https://ncbi.nlm.nih.gov/pubmed/19846775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910218106
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