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Endothelial siRNA delivery in nonhuman primates using ionizable low–molecular weight polymeric nanoparticles
Dysfunctional endothelial cells contribute to the pathophysiology of many diseases, including vascular disease, stroke, hypertension, atherosclerosis, organ failure, diabetes, retinopathy, and cancer. Toward the goal of creating a new RNA-based therapy to correct aberrant endothelial cell gene expre...
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| Publicado no: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6021147/ https://ncbi.nlm.nih.gov/pubmed/29963629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar8409 |
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