Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA

Marburg virus (MARV) and the closely related filovirus Ebola virus cause severe and often fatal hemorrhagic fever (HF) in humans and nonhuman primates with mortality rates up to 90%. There are no vaccines or drugs approved for human use, and no postexposure treatment has completely protected nonhuma...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Thi, Emily P., Mire, Chad E., Ursic-Bedoya, Raul, Geisbert, Joan B., Lee, Amy C. H., Agans, Krystle N., Robbins, Marjorie, Deer, Daniel J., Fenton, Karla A., MacLachlan, Ian, Geisbert, Thomas W.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502585/
https://ncbi.nlm.nih.gov/pubmed/25143366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009706
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