siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Ebolaviruses and marburgviruses belong to the family Filoviridae and cause high lethality in infected patients. There are currently no licensed filovirus vaccines or antiviral therapies. The development of broad-spectrum therapies against members of the Marburgvirus genus, including Marburg virus (M...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Thi, Emily P., Mire, Chad E., Lee, Amy C.H., Geisbert, Joan B., Ursic-Bedoya, Raul, Agans, Krystle N., Robbins, Marjorie, Deer, Daniel J., Cross, Robert W., Kondratowicz, Andrew S., Fenton, Karla A., MacLachlan, Ian, Geisbert, Thomas W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707162/
https://ncbi.nlm.nih.gov/pubmed/29106386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96185
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