siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Ebolaviruses and marburgviruses belong to the family Filoviridae and cause high lethality in infected patients. There are currently no licensed filovirus vaccines or antiviral therapies. The development of broad-spectrum therapies against members of the Marburgvirus genus, including Marburg virus (M...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Thi, Emily P., Mire, Chad E., Lee, Amy C.H., Geisbert, Joan B., Ursic-Bedoya, Raul, Agans, Krystle N., Robbins, Marjorie, Deer, Daniel J., Cross, Robert W., Kondratowicz, Andrew S., Fenton, Karla A., MacLachlan, Ian, Geisbert, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707162/
https://ncbi.nlm.nih.gov/pubmed/29106386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96185
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