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Copper-promoted site-selective carbonylation of sp(3) and sp(2) C–H bonds with nitromethane

Copper-promoted direct carbonylation of unactivated sp(3) C–H and aromatic sp(2) C–H bonds of amides was developed using nitromethane as a novel carbonyl source. The sp(3) C–H functionalization showed high site-selectivity by favoring the C–H bonds of α-methyl groups. The sp(2) C–H carbonylation fea...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Wu, Xuesong, Miao, Jinmin, Li, Yanrong, Li, Guigen, Ge, Haibo
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020547/
https://ncbi.nlm.nih.gov/pubmed/30155175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc01087c
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