Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

Ketamine, a racemic mixture consisting of (S)- and (R)-ketamine, has been in clinical use since 1970. Although best characterized for its dissociative anesthetic properties, ketamine also exerts analgesic, anti-inflammatory, and antidepressant actions. We provide a comprehensive review of these ther...

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Gepubliceerd in:Pharmacol Rev
Hoofdauteurs: Zanos, Panos, Moaddel, Ruin, Morris, Patrick J., Riggs, Lace M., Highland, Jaclyn N., Georgiou, Polymnia, Pereira, Edna F. R., Albuquerque, Edson X., Thomas, Craig J., Zarate, Carlos A., Gould, Todd D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2018
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Review Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020109/
https://ncbi.nlm.nih.gov/pubmed/29945898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.117.015198
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