Computer-Aided Discovery of Two Novel Chalcone-Like Compounds Active and Selective Against Leishmania infantum

Leishmaniasis are infectious diseases caused by parasites of genus Leishmania that affects 12 million people in 98 countries mainly in Africa, Asia, and Latin America. Effective treatments for this disease are urgently needed. In this study, we present a computer-aided approach to investigate a set...

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Detalles Bibliográficos
Publicado en:Bioorg Med Chem Lett
Main Authors: Gomes, Marcelo N., Alcântara, Laura M., Neves, Bruno J., Melo-Filho, Cleber C., Freitas-Junior, Lucio H., Moraes, Carolina B., Ma, Rui, Franzblau, Scott G., Muratov, Eugene N., Andrade, Carolina Horta
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020026/
https://ncbi.nlm.nih.gov/pubmed/28434763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.04.010
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