Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania (NTD) endemic in 98 countries. Although some drugs are available, current treatments deal with issues such as toxicity, low efficacy, and emergence of resistance. Therefore, there is an urgent need to identify...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Borba, Joyce V.B., Silva, Arthur C., Ramos, Pablo I.P., Grazzia, Nathalia, Miguel, Danilo C., Muratov, Eugene N., Furnham, Nicholas, Andrade, Carolina H.
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429582/
https://ncbi.nlm.nih.gov/pubmed/30949306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.02.005
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