Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania (NTD) endemic in 98 countries. Although some drugs are available, current treatments deal with issues such as toxicity, low efficacy, and emergence of resistance. Therefore, there is an urgent need to identify...

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Bibliografiske detaljer
Udgivet i:Comput Struct Biotechnol J
Main Authors: Borba, Joyce V.B., Silva, Arthur C., Ramos, Pablo I.P., Grazzia, Nathalia, Miguel, Danilo C., Muratov, Eugene N., Furnham, Nicholas, Andrade, Carolina H.
Format: Artigo
Sprog:Inglês
Udgivet: Research Network of Computational and Structural Biotechnology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429582/
https://ncbi.nlm.nih.gov/pubmed/30949306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.02.005
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