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Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer
Application of advanced intravital imaging facilitates dynamic monitoring of pathway activity upon therapeutic inhibition. Here, we assess resistance to therapeutic inhibition of the PI3K pathway within the hypoxic microenvironment of pancreatic ductal adenocarcinoma (PDAC) and identify a phenomenon...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cell Press
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6019737/ https://ncbi.nlm.nih.gov/pubmed/29898401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.038 |
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