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Repair of triplex-directed DNA alkylation by nucleotide excision repair

Triplex-forming oligonucleotides (TFOs) are being investigated as highly specific DNA binding agents to inhibit the expression of clinically relevant genes. So far, they have been shown to inhibit transcription from the HER-2/neu gene in vitro, whereas their use in vivo has been studied to a limited...

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Detalhes bibliográficos
Main Authors: Ziemba, Amy, Derosier, L. Chris, Methvin, Russell, Song, Chun-Yan, Clary, Eric, Kahn, Wendy, Milesi, David, Gorn, Vladimir, Reed, Mike, Ebbinghaus, Scot
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60196/
https://ncbi.nlm.nih.gov/pubmed/11691913
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