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Repair of triplex-directed DNA alkylation by nucleotide excision repair

Triplex-forming oligonucleotides (TFOs) are being investigated as highly specific DNA binding agents to inhibit the expression of clinically relevant genes. So far, they have been shown to inhibit transcription from the HER-2/neu gene in vitro, whereas their use in vivo has been studied to a limited...

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Main Authors: Ziemba, Amy, Derosier, L. Chris, Methvin, Russell, Song, Chun-Yan, Clary, Eric, Kahn, Wendy, Milesi, David, Gorn, Vladimir, Reed, Mike, Ebbinghaus, Scot
格式: Artigo
語言:Inglês
出版: Oxford University Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC60196/
https://ncbi.nlm.nih.gov/pubmed/11691913
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