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Repair of triplex-directed DNA alkylation by nucleotide excision repair

Triplex-forming oligonucleotides (TFOs) are being investigated as highly specific DNA binding agents to inhibit the expression of clinically relevant genes. So far, they have been shown to inhibit transcription from the HER-2/neu gene in vitro, whereas their use in vivo has been studied to a limited...

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Détails bibliographiques
Auteurs principaux: Ziemba, Amy, Derosier, L. Chris, Methvin, Russell, Song, Chun-Yan, Clary, Eric, Kahn, Wendy, Milesi, David, Gorn, Vladimir, Reed, Mike, Ebbinghaus, Scot
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC60196/
https://ncbi.nlm.nih.gov/pubmed/11691913
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