Bipartite substrate discrimination by human nucleotide excision repair

Mammalian nucleotide excision repair (NER) eliminates carcinogen–DNA adducts by double endonucleolytic cleavage and subsequent release of 24–32 nucleotide-long single-stranded fragments. Here we manipulated the deoxyribose–phosphate backbone of DNA to analyze the mechanism by which damaged strands a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hess, Martin T., Schwitter, Urs, Petretta, Mario, Giese, Bernd, Naegeli, Hanspeter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6664
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