Direct association of Bloom’s syndrome gene product with the human mismatch repair protein MLH1

Bloom’s syndrome (BS) is a rare genetic disorder characterised by genomic instability and cancer susceptibility. BLM, the gene mutated in BS, encodes a member of the RecQ family of DNA helicases. Here, we identify hMLH1, which is involved in mismatch repair (MMR) and recombination, as a protein that...

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Detalhes bibliográficos
Main Authors: Pedrazzi, Graziella, Perrera, Claudia, Blaser, Heiko, Kuster, Patrick, Marra, Giancarlo, Davies, Sally L., Ryu, Gi-Hyuck, Freire, Raimundo, Hickson, Ian D., Jiricny, Josef, Stagljar, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60193/
https://ncbi.nlm.nih.gov/pubmed/11691925
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