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Direct association of Bloom’s syndrome gene product with the human mismatch repair protein MLH1

Bloom’s syndrome (BS) is a rare genetic disorder characterised by genomic instability and cancer susceptibility. BLM, the gene mutated in BS, encodes a member of the RecQ family of DNA helicases. Here, we identify hMLH1, which is involved in mismatch repair (MMR) and recombination, as a protein that...

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Udgivet i:Nucleic Acids Res
Principais autores: Pedrazzi, Graziella, Perrera, Claudia, Blaser, Heiko, Kuster, Patrick, Marra, Giancarlo, Davies, Sally L., Ryu, Gi-Hyuck, Freire, Raimundo, Hickson, Ian D., Jiricny, Josef, Stagljar, Igor
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691925/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.21.4378
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