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A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export

HIV-1 Rev mediates the nuclear export of unspliced and partially-spliced viral transcripts for the production of progeny genomes and structural proteins. In this process, four (or more) copies of Rev assemble onto a highly-structured 351-nt region in such viral transcripts, the Rev response element...

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Detalles Bibliográficos
Publicado en:J Struct Biol
Main Authors: Watts, Norman R., Eren, Elif, Zhuang, Xiaolei, Wang, Yun-Xing, Steven, Alasdair C., Wingfield, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019186/
https://ncbi.nlm.nih.gov/pubmed/29605570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2018.03.011
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