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RNA-guided assembly of Rev-RRE nuclear export complexes

HIV replication requires nuclear export of unspliced and singly spliced viral transcripts. Although a unique RNA structure has been proposed for the Rev-response element (RRE) responsible for viral mRNA export, how it recruits multiple HIV Rev proteins to form an export complex has been unclear. We...

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Hlavní autoři: Bai, Yun, Tambe, Akshay, Zhou, Kaihong, Doudna, Jennifer A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142337/
https://ncbi.nlm.nih.gov/pubmed/25163983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03656
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